Paxillin is a process involving cell adhesion extracellular matrix (focal adhesion) sites on the actin – membrane attached to the cytoskeleton. Paxillin in integrin signaling plays a very important role in integrin-mediated cytoskeletal re-organization needs to paxillin phosphorylation of tyrosine residues. Paxillin is focal adhesion kinase (FAK) in its 118 tyrosine residues at the phosphorylation. Has proven, paxillin 118-bit and 31 two phosphorylation of tyrosine residues for MM1 cancer cell migration is necessary. Paxillin is a molecular weight of 68KDa the focal adhesion protein involved in tumor cell adhesion and metastasis. Mainly used for a variety of cancer research.
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