Ceftiofur Hydrochloride (CAS 103980-44-5) Description

Synonym:    Excede

CAS Number:   103980-44-5

Purity: ≥94%

Molecular Weight:  560.02

Molecular Formula:  C19H17N5O7S3•HCl

Solubility:  Soluble in methanol, water (<1 mg/ml at 25° C), DMSO (112 mg/ml at 25° C), and ethanol (40 mg/ml at 25° C).

Melting Point: > 184° C (dec.)

Boiling Point:   >232° C

Application:  A cephalosporin antibiotic resistant to beta-lactamase

Storage: Store at room temperature

Description:

Ceftiofur Hydrochloride is the hydrochloride alkali anatomy of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity. Ceftiofur binds to and inactivates penicillin-binding proteins (PBPs) amid on the close film of the bacterial corpuscle wall. PBPs are enzymes complex in the terminal stages of accumulating the bacterial corpuscle bank and in about-face the corpuscle bank during advance and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains all-important for bacterial corpuscle bank backbone and rigidity. This after-effects in the abrasion of the bacterial corpuscle bank and causes corpuscle lysis.