What is histamine dihydrochloride used for?

Histamine dihydrochloride use in leukemia

Histamine dihydrochloride is an amine acquired by enzymatic decarboxylation of HISTIDINE. It is a able analeptic of belly secretion, a constrictor of bronchial bland muscle, a vasodilator, and aswell a centrally acting neurotransmitter.

Histamine dihydrochloride is administered in affiliation with low doses of the immune-activating cytokine interleukin-2 (IL-2) in the post-remission appearance of AML, i.e. if patients accept completed the antecedent chemotherapy. This aggregate has been appear to decidedly abate the accident of backsliding in AML. The effect is decidedly arresting in patients in their aboriginal absolution who are beneath the age of 60.

The aggregate of histamine dihydrochloride and interleukin-2 was accustomed for use in AML patients aural the European Union in October 2008 and will be marketed in the EU by the Swedish biologic aggregation Meda. The biologic is aswell accessible through a called accommodating affairs in several added countries (excluding the US).