Unoprostone Descriptions

Unoprostone is used to amusement added burden in the eye acquired by open-angle glaucoma. It is aswell used to amusement a activity alleged ocular hypertension (hypertension of the eye).

Unoprostone is believed to abate animated intraocular burden (IOP), by accretion the address of aqueous humor. The apparatus of activity for the IOP-lowering aftereffect of unoprostone is controversial. Early studies showed that unoprostone increases aqueous amusement address through the uveoscleral alleyway agnate to the 20-carbon prostaglandin analogs, such as latanoprost.8 More contempo evidence, however, shows that it may work, at atomic in part, through dispatch of Ca2+-activated BK and CIC-2 blazon channels, arch to added trabecular cobweb outflow.